116 Results for "

Schisandra arisanensis Hayata Ic.

" in MedChemExpress (MCE) Product Catalog:
Products (116)

116 Results for "Schisandra arisanensis Hayata Ic." in MCE Product Catalog:

44
Indocyanine green
Indocyanine green
0 Images
44 Publications Verification
Cat. No.: HY-D0711
CAS No.: 3599-32-4
Synonyms: Foxgreen; IC Green; Cardiogreen
Indocyanine green (Foxgreen) is a low toxicic fluorescent agent that has been widely used in medical diagnostics, such as determining cardiac output, hepatic function, and liver blood flow, and for ophthalmic angiography (Ex/Em = 785/813 nm) .
24
Rabusertib
Rabusertib
0 Images
24 Cited Publications
Cat. No.: HY-14720
CAS No.: 911222-45-2
Purity:  99.98%
Synonyms: LY2603618; IC-83
Target:  

Checkpoint Kinase (Chk) Autophagy

Research Areas:  

Cancer

Rabusertib (LY2603618) is a potent and selective inhibitor of Chk1 with an IC50 of 7 nM.
13
Cepharanthine
Cepharanthine
0 Images
13 Cited Publications
Cat. No.: HY-N6972
CAS No.: 481-49-2
Category:  

Infection Alkaloids Stephania cepharantha Hayata Plants Disease Research Fields Isoquinoline Alkaloids Inflammation/Immunology Menispermaceae Stephania japonica (Thunb.) Miers

Target:  

Autophagy SARS-CoV Cytochrome P450 Apoptosis Parasite

Cepharanthine is a natural product that can be isolated from the plant Stephania cephalantha Hayata. Cepharanthine has anti-severe acute respiratory syndrome coronavirus 2 (anti-SARS-CoV-2) activities. Cepharanthine has good effective in suppressing viral proliferation (half maximal (50%) inhibitory concentration (IC50) and 90% inhibitory concentration (IC90) values of 1.90 and 4.46 μM . Cepharanthine can also effectively reverses P-gp-mediated multidrug resistance in K562 cells and increase enhances the sensitivity of anticancer agents in xenograft mice model . Cepharanthine shows inhibitory effects of human liver cytochrome P450 enzymes CYP3A4, CYP2E1 and CYP2C9. Cepharanthine has antitumor, anti-inflammatory and antinociceptive effects .
11
Schisandrin B
Schisandrin B
0 Images
11 Cited Publications
Cat. No.: HY-N0089
CAS No.: 61281-37-6
Synonyms: γ-Schisandrin; Wuweizisu B
Category:  

Neurological Disease Lignans Phenylpropanoids Plants Schisandraceae Disease Research Fields Schisandra chinensis (Turcz.) Baill. Cancer

Target:  

Autophagy Reactive Oxygen Species (ROS)

Schisandrin B (γ-Schisandrin) is a biphenylcyclooctadiene derivative isolated from Schisandra chinensis and has been shown to have antioxidant effects on the liver and heart of rodents.
9
Tadalafil
Tadalafil
0 Images
9 Cited Publications
Cat. No.: HY-90009A
CAS No.: 171596-29-5
Synonyms: IC-351
Target:  

Phosphodiesterase (PDE) Apoptosis

Research Areas:  

Cardiovascular Disease Cancer

Tadalafil (IC-351) is a PDE5 inhibitor with an IC50 value of 1.8 nM.
5
Momordin Ic
Momordin Ic
0 Images
5 Cited Publications
Cat. No.: HY-N0330
CAS No.: 96990-18-0
Category:  

Kochia scoparia L. Schrad. Triterpenes Terpenoids Plants Disease Research Fields Cancer Chenopodiaceae

Target:  

Apoptosis Autophagy PI3K c-Myc

Momordin Ic is an orally active triterpenoid saponin that can be isolated from Kochia scoparia. It is also a SUMO specific protease 1 (SENP1) inhibitor, SENP1/c-MYC signaling pathway inhibitor, and apoptosis inducer. Momordin Ic induces autophagy and apoptosis in liver cancer cells through the PI3K/Akt and MAPK signaling pathways mediated by reactive oxygen species. Momordin Ic has the ability to control glucose induced blood glucose elevation, inhibit gastric emptying, resist rheumatoid arthritis, reduce CCl4 (HY-Y0298) induced hepatotoxicity and anti-tumor activity .
4
IC261
IC261
0 Images
4 Cited Publications
Cat. No.: HY-12774
CAS No.: 186611-52-9
Purity:  99.54%
Target:  

Casein Kinase Apoptosis

Research Areas:  

Cancer

IC261 is a selective, ATP-competitive CK1 inhibitor, with IC50s of 1 μM, 1 μM, 16 μM for Ckiδ, Ckiε and Ckiα1, respectively.
3
Schisandrin
Schisandrin
0 Images
3 Cited Publications
Cat. No.: HY-N0691
CAS No.: 7432-28-2
Synonyms: Schizandrin; Schizandrol; Schizandrol-A
Category:  

Lignans Phenylpropanoids Plants Schisandraceae Disease Research Fields Schisandra chinensis (Turcz.) Baill. Cancer

Target:  

Autophagy

Schisandrin (Schizandrin), a dibenzocyclooctadiene lignan, is isolated from the fruit of Schisandra chinensis Baill. Schisandrin exhibits antioxidant, hepatoprotective, anti-cancer and anti-inflammatory activities. Schisandrin also can reverses memory impairment in rats .
3
IC-87114
IC-87114
0 Images
3 Cited Publications
Cat. No.: HY-10110
CAS No.: 371242-69-2
Purity:  99.85%
Target:  

PI3K

Research Areas:  

Cancer

IC-87114 is a potent and selective PI3Kδ inhibitor with IC50 of 0.5 μM.
3
Gomisin J
Gomisin J
0 Images
3 Cited Publications
Cat. No.: HY-N0385
CAS No.: 66280-25-9
Category:  

Cardiovascular Disease Monophenols Lignans Phenols Phenylpropanoids Plants Schisandraceae Disease Research Fields Schisandra chinensis (Turcz.) Baill.

Target:  

NO Synthase AMPK CaMK NF-κB Keap1-Nrf2

Gomisin J is a Schisandra chinensis-derived lignan that can inhibit multiple targets such as eNOS, AMPK (LKB1, CaMKIIβ), fetuin-A, NF-κB, Nrf2/HO-1, and can pass through the blood-brain barrier. Gomisin J increases NO bioavailability by activating eNOS, regulates lipid metabolism by activating the AMPK pathway, inhibits fetuin-A and NF-κB to exert anti-inflammatory effects, and activates Nrf2/HO-1 to enhance antioxidant capacity. Gomisin J has the activities of anti-hypertension, regulating liver lipid metabolism, and reducing cerebral ischemia-reperfusion injury, and can be used for research on hypertension, non-alcoholic fatty liver disease, cerebral ischemia-reperfusion injury, etc .
2
Schisandrol B
Schisandrol B
0 Images
2 Cited Publications
Cat. No.: HY-N0692
CAS No.: 58546-54-6
Synonyms: Gomisin-A; TJN-101; Wuweizi alcohol-B
Category:  

Lignans Phenylpropanoids Plants Schisandraceae Disease Research Fields Schisandra chinensis (Turcz.) Baill. Cancer

Target:  

Reactive Oxygen Species (ROS) Cytochrome P450 Autophagy

Schisandrol B (Gomisin-A) is a major active constituent of Schisandra chinensis with hepato-protective effects. Schisandrol B inhibits reactive oxygen species (ROS) production. Schisandrol B inhibits the activity of P-glycoprotein and CYP3A and also has anti-inflammatory, anti-diabetic and antioxidant activities .
2
Atibuclimab
Atibuclimab
0 Images
2 Cited Publications
Cat. No.: HY-P99008
CAS No.: 2417175-94-9
Synonyms: IC14

Target:  

Toll-like Receptor (TLR)

Research Areas:  

Infection Neurological Disease Inflammation/Immunology

Atibuclimab (IC14), is a chimeric monoclonal antibody directed against CD14 and is composed of murine variable and human IgG4 Fc regions. Atibuclimab attenuates Lipopolysaccharides (HY-D1056) (LPS)-induced symptoms and strongly inhibits LPS-induced proinflammatory cytokine release, while only delaying the release of the anti-inflammatory cytokines soluble TNF receptor type I and IL-1 receptor antagonist. Atibuclimab can be used for the research of amyotrophic lateral sclerosis, sepsis, community-acquired pneumonia, or acute lung injury .
2
IC87201
IC87201
0 Images
2 Cited Publications
Cat. No.: HY-100457
CAS No.: 866927-10-8
Purity:  97.24%
Target:  

iGluR

Research Areas:  

Neurological Disease

IC87201, an inhibitor of PSD95-nNOS protein-protein interactions, suppresses NMDAR-dependent NO and cGMP formation.
1
Chicanine
Chicanine
0 Images
1 Cited Publications
Cat. No.: HY-N2270
CAS No.: 78919-28-5
Category:  

Monophenols Lignans Phenols Phenylpropanoids Plants Schisandraceae Disease Research Fields Inflammation/Immunology Schisandra chinensis (Turcz.) Baill.

Target:  

p38 MAPK ERK IKK

Chicanine is a lignan compound of Schisandra chinesis, inhibits LPS-induced phosphorylation of p38 MAPK, ERK 1/2 and IκB-α, with anti-inflammatory activity .
1
Angeloylgomisin O
Angeloylgomisin O
0 Images
1 Cited Publications
Cat. No.: HY-N2271
CAS No.: 83864-69-1
Category:  

Lignans Phenylpropanoids Plants Schisandraceae Disease Research Fields Inflammation/Immunology Schisandra chinensis (Turcz.) Baill.

Target:  

Others

Angeloylgomisin O, a lignin extract of Schisandra rubriflora. Anti-inflammatory properties .
1
Schisantherin B
Schisantherin B
0 Images
1 Cited Publications
Cat. No.: HY-N0695
CAS No.: 58546-55-7
Synonyms: Gomisin-B; Wuweizi ester-B; Schisantherin-B
Category:  

Lignans Phenylpropanoids Plants Schisandraceae Disease Research Fields Inflammation/Immunology Schisandra chinensis (Turcz.) Baill.

Target:  

PI3K Akt mTOR GSK-3 Tau Protein TNF Receptor Interleukin Related Apoptosis

Schisantherin B (Gomisin-B) is a lignan compound and one of the active components of Schisandra chinensis. Schisantherin B activates the PI3K/AKT signaling pathway, restores the activity of GSK3β, and reduces the hyperphosphorylation of tau protein in hippocampal and cerebral cortical tissues. Schisantherin B upregulates the level of GLT-1, decreases the expression of pro-inflammatory cytokines TNF-α/IL-1β/IL-6, upregulates the expression of IL-10, and inhibits cell apoptosis. Schisantherin B is applicable to the research of spinal cord injury, Alzheimer's disease and depression .
Angeloylgomisin H
Angeloylgomisin H
0 Images
Cat. No.: HY-N2209
CAS No.: 66056-22-2
Category:  

Lignans Metabolic Disease Phenylpropanoids Plants Schisandraceae Disease Research Fields Schisandra chinensis (Turcz.) Baill.

Target:  

PPAR

Angeloylgomisin H, as a major lignin extract of Schisandra rubriflora, has the potential to improve insulin-stimulated glucose uptake by activating PPAR-γ .
Indocyanine green (Standard)
Indocyanine green (Standard)
0 Images
Cat. No.: HY-D0711R
CAS No.: 3599-32-4
Synonyms: Foxgreen (Standard); IC Green (Standard); Cardiogreen (Standard)
Indocyanine green (Standard) is the analytical standard of Indocyanine green. This product is intended for research and analytical applications. Indocyanine green (Foxgreen) is a low toxicic fluorescent agent that has been widely used in medical diagnostics, such as determining cardiac output, hepatic function, and liver blood flow, and for ophthalmic angiography .
Schisandrone
Schisandrone
0 Images
Cat. No.: HY-N2245
CAS No.: 98619-25-1
Category:  

Monophenols Lignans Phenols Phenylpropanoids Plants Schisandraceae Disease Research Fields Schisandra chinensis (Turcz.) Baill. Cancer

Target:  

CD74

Schisandrone, a 4-aryltetralone lignan, is isolated from the dried fruits of Schisandra sphenanthera . Schisandrone is an alpha-hemolysin (Hla) inhibitor that downregulates the transcript levels of hla, agrA and RNAIII. Hla is an integral virulence determinant in Staphylococcus aureus that determines pathogenicity. Schisandrone is a potent inhibitor against MRSA pneumonia .
Tadalafil-d3
Tadalafil-d3
0 Images
Cat. No.: HY-90009S
CAS No.: 960226-55-5
Synonyms: IC-351-d3
Tadalafil-d3 is the deuterium labeled Nortadalafil. Nortadalafil is demethyl Tadalafil, which is a PDE5 inhibitor, currently marketed in pill form for treating erectile dysfunction (ED) under the name Cialis; and under the name Adcirca for the treatment of pulmonary arterial hypertension.
Assay Types